Analytical Data
-
基因名
LRSAM1
- Application
-
别名
CMT2P; E3 ubiquitin protein ligase LRSAM1; E3 ubiquitin-protein ligase LRSAM1; EC 6.3.2.-; FLJ31641 ; hTAL; Leucine rich repeat and sterile alpha motif containing 1; Leucine rich repeat and sterile alpha motif containing protein 1; Leucine-rich repeat and sterile alpha motif-containing protein 1; LRSAM1; LRSM1_HUMAN
-
种属
Human
-
表达系统
E. coli
-
标签
His
-
纯度
Greater than 90% as determined by SDS-PAGE.
-
蛋白编号
Q6UWE0
-
表达区间
1-723aa
-
氨基酸序列
MPLFFRKRKPSEEARKRLEYQMCLAKEAGADDILDISKCELSEIPFGAFATCKVLQKKVLIVHTNHLTSLLPKSCSLLSLATIKVLDLHDNQLTALPDDLGQLTALQVLNVERNQLMQLPRSIGNLTQLQTLNVKDNKLKELPDTVGELRSLRTLNISGNEIQRLPQMLAHVRTLEMLSLDASAMVYPPREVCGAGTAAILQFLCKESGLEYYPPSQYLLPILEQDGIENSRDSPDGPTDRFSREELEWQNRFSDYEKRKEQKMLEKLEFERRLELGQREHTQLLQQSSSQKDEILQTVKEEQSRLEQGLSEHQRHLNAERQRLQEQLKQTEQNISSRIQKLLQDNQRQKKSSEILKSLENERIRMEQLMSITQEETESLRRRDVASAMQQMLTESCKNRLIQMAYESQRQNLVQQACSSMAEMDERFQQILSWQQMDQNKAISQILQESAMQKAAFEALQVKKDLMHRQIRSQIKLIETELLQLTQLELKRKSLDTESLQEMISEQRWALSSLLQQLLKEKQQREEELREILTELEAKSETRQENYWLIQYQRLLNQKPLSLKLQEEGMERQLVALLEELSAEHYLPIFAHHRLSLDLLSQMSPGDLAKVGVSEAGLQHEILRRVQELLDAARIQPELKPPMGEVVTPTAPQEPPESVRPSAPPAELEVQASECVVCLEREAQMIFLNCGHVCCCQQCCQPLRTCPLCRQDIAQRLRIYHSS
-
分子量
83 kDa
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
-
性状
Freeze-dried powder
-
缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
-
稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Identification
Protein Description
LRSAM1, or Leucine-Rich Repeat and SH3 Domain Containing 1, is a protein associated with a range of cellular processes, including membrane trafficking, autophagy, and the immune response. Research into LRSAM1 has gained prominence due to its role in various diseases, particularly in neurodegenerative disorders and cancers. Recent studies have suggested that mutations in the LRSAM1 gene can disrupt its normal function, potentially leading to pathological conditions. The protein contains several functional domains that mediate protein-protein interactions and involvement in the ubiquitin-proteasome pathway, making it a key player in cellular signaling and homeostasis. The recombinant expression of LRSAM1 is crucial for elucidating its structure-function relationships and understanding the mechanistic basis of its involvement in disease. By producing this recombinant protein, researchers aim to explore its biochemical properties and interactions with other cellular factors, which could provide insights into the development of therapeutic strategies targeting LRSAM1-related pathways. Furthermore, investigating LRSAM1's role in immune responses can advance our understanding of its potential as a biomarker or therapeutic target in immune-related conditions. Overall, the study of LRSAM1 and its recombinant forms is integral to unraveling its biological significance and potential implications in health and disease.
