Analytical Data
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基因名
SFTA2
- Application
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别名
SFTA2;COLEC5;PSAP;SFTP1;Pulmonary surfactant-associated Protein A2
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q6UW10
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表达区间
20-78aa
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氨基酸序列
TGPGMTLQLKLKESFLTNSSYESSFLELLEKLCLLLHLPSGTSVTLHHARSQHHVVCNT
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分子量
13.5 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
SFTA2, or Surfactant Protein A2, is a member of the surfactant protein family that plays a crucial role in pulmonary surfactant function, innate immunity, and the maintenance of alveolar integrity. Research has highlighted its importance in various lung diseases, including pulmonary fibrosis, chronic obstructive pulmonary disease (COPD), and neonatal respiratory distress syndrome. Due to its significant role in maintaining lung homeostasis, SFTA2 has emerged as a target for therapeutic strategies aimed at enhancing surfactant function and modulating immune responses in the lungs. The recombinant expression of SFTA2 proteins allows for the detailed study of their structure-function relationships and provides a platform for potential therapeutic applications. Advances in genetic engineering techniques have enabled the production of recombinant SFTA2 proteins, facilitating investigations into their molecular mechanisms and biological activities. Furthermore, understanding the protein's role in surfactant metabolism and immune response can lead to the development of novel interventions for lung pathologies, enhancing our ability to treat respiratory diseases effectively. Overall, the ongoing research surrounding recombinant SFTA2 proteins is pivotal for uncovering new therapies aimed at improving lung function and patient outcomes in respiratory conditions.












