Analytical Data
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Gene name
LRRC27
- Application
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Alternative Names
LRRC27; KIAA1674; Leucine-rich repeat-containing protein 27
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9C0I9
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Expression Region
1-530aa
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AA Sequence
MEGSSSYEVP SVAAADLEEG AGQTRSLPAT PSKDVHKGVG GIIFSSSPIL DLSESGLCRL EEVFRIPSLQ QLHLQRNALC VIPQDFFQLL PNLTWLDLRY NRIKALPSGI GAHQHLKTLL LERNPIKMLP VELGSVTTLK ALNLRHCPLE FPPQLVVQKG LVAIQRFLRM WAVEHSLPRN PTSQEAPPVR EMTLRDLPSP GLELSGDHAS NQGAVNAQDP EGAVMKEKAS FLPPVEKPDL SELRKSADSS ENWPSEEEIR RFWKLRQEIV EHVKADVLGD QLLTRELPPN LKAALNIEKE LPKPRHVFRR KTASSRSILP DLLSPYQMAI RAKRLEESRA AALRELQEKQ ALMEQQRREK RALQEWRERA QRMRKRKEEL SKLLPPRRSM VASKIPSATD LIDNRKVPLN PPGKMKPSKE KSPQASKEMS ALQERNLEEK IKQHVLQMRE QRRFHGQAPL EEMRKAAEDL EIATELQDEV LKLKLGLTLN KDRRRAALTG NLSLGLPAAQ PQNTFFNTKY GESGNVRRYQ
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Molecular Weight
60 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
LRRC27 (Leucine-Rich Repeat Containing 27) is a gene encoding a protein involved in various cellular processes, including signal transduction and protein-protein interactions. Recent studies have highlighted its significance in several biological functions, particularly in the context of neuronal development and synaptic transmission. As a member of the leucine-rich repeat family, LRRC27 plays a crucial role in the assembly and maintenance of synapses, which are essential for effective communication between neurons. Aberrations in LRRC27 expression have been linked to neurological disorders, making it a potential target for therapeutic intervention. To better understand the functional mechanisms of LRRC27, researchers have focused on the production of recombinant LRRC27 protein, which allows for the investigation of its structure, interactions, and activity in vitro. This foundational research aims to elucidate its role in synaptic function and neurodevelopment, potentially unveiling new insights into its involvement in neurodegenerative diseases and offering avenues for novel treatments. Through the expression and characterization of LRRC27 recombinant protein, scientists aspire to bridge the knowledge gap surrounding this protein's contributions to neuronal health and disease.
