Analytical Data
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Gene name
LRRC14
- Application
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Alternative Names
LRRC14; KIAA0014; Leucine-rich repeat-containing protein 14
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Species
Human
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Source
E. coli
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Tag
GST-tag at N-terminal
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q15048
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Expression Region
1-493aa
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AA Sequence
MHTLVFLSTRQVLQCQPAACQALPLLPRELFPLLFKVAFMDKKTVVLRELVHTWPFPLLSFQQLLQECAHCSRALLQERPSTESMQAVILGLTARLHTSEPGASTQPLCRKHALRVLDMTGLLDDGVEQDPGTMSMWDCTAAVARTCIAQQQGGAAEPGPAPIPVEVRVDLRVNRASYAFLREALRSSVGSPLRLCCRDLRAEDLPMRNTVALLQLLDAGCLRRVDLRFNNLGLRGLSVIIPHVARFQHLASLRLHYVHGDSRQPSVDGEDNFRYFLAQMGRFTCLRELSMGSSLLSGRLDQLLSTLQSPLESLELAFCALLPEDLRFLARSPHAAHLKKLDLSGNDLSGSQLAPFQGLLQASAATLLHLELTECQLADTQLLATLPILTQCASLRYLGLYGNPLSMAGLKELLRDSVAQAELRTVVHPFPVDCYEGLPWPPPASVLLEASINEEKFARVEAELHQLLLASGRAHVLWTTDIYGRLAADYFSL
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Molecular Weight
80.9 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
LRRC14 (Leucine-Rich Repeat Containing 14) is a protein that has gained attention in recent years due to its potential role in various cellular processes and its implications in health and disease. Initial studies suggest that LRRC14 may function as a regulator of signaling pathways and cellular communication, impacting processes such as cell growth, differentiation, and apoptosis. The protein contains a series of leucine-rich repeats, which are known to facilitate protein-protein interactions and play critical roles in the structural integrity and functionality of numerous cellular complexes. Given its association with important biological functions, researchers are particularly interested in the involvement of LRRC14 in neurodevelopmental disorders and its potential implications in cancer biology. Furthermore, the generation of recombinant LRRC14 protein allows for detailed biochemical analyses, enabling scientists to dissect its functional properties and interactions in vitro. Understanding the role of LRRC14 and its mechanisms of action could provide insights into novel therapeutic strategies for diseases where this protein is implicated, paving the way for further investigations aimed at elucidating its biological significance and potential applications in regenerative medicine and targeted therapies.
