Analytical Data
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Gene name
ACTg2
- Application
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Alternative Names
ACTg2；ACTA3；ACTL3；ACTSG；Actin. gamma-enteric smooth muscle
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P63267
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Expression Region
3-376aa
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AA Sequence
EEETTALV CDNGSGLCKA GFAGDDAPRA VFPSIVGRPR HQGVMVGMGQ KDSYVGDEAQ SKRGILTLKY PIEHGIITNW DDMEKIWHHS FYNELRVAPE EHPTLLTEAP LNPKANREKM TQIMFETFNV PAMYVAIQAV LSLYASGRTT GIVLDSGDGV THNVPIYEGY ALPHAIMRLD LAGRDLTDYL MKILTERGYS FVTTAEREIV RDIKEKLCYV ALDFENEMAT AASSSSLEKS YELPDGQVIT IGNERFRCPE TLFQPSFIGM ESAGIHETTY NSIMKCDIDI RKDLYANNVL SGGTTMYPGI ADRMQKEITA LAPSTMKIKI IAPPERKYSV WIGGSILASL STFQQMWISK PEYDEAGPSI VHRKCF
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Molecular Weight
41.8 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
ACTg2, or the actin gamma-2 protein, is a key component of the cytoskeletal structure in smooth muscle cells and is critical for maintaining the contractile function of these cells. Research on ACTg2 has gained prominence due to its significant role in various physiological processes such as vascular contraction and gastrointestinal motility. Mutations or dysregulation of ACTg2 have been implicated in a range of pathologies, including congenital disorders affecting smooth muscle function and certain forms of cancer. The recombinant production of ACTg2 has enabled detailed studies of its structural and functional properties, facilitating insights into its interaction with other cytoskeletal proteins and cellular signaling pathways. Understanding the mechanisms governing ACTg2 activity can illuminate the underlying causes of smooth muscle-related diseases and pave the way for developing targeted therapies. Recent advancements in biotechnological methods have also improved the purification and characterization of ACTg2, which are essential for both basic research and potential clinical applications. Consequently, ACTg2 serves as a compelling model for studying smooth muscle dynamics, with implications extending to muscular development and the pathophysiology of smooth muscle disorders.
