Cat: PA2000-8855

Recombinant Human LBX2 Protein,GST

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Analytical Data

  • 基因名

    LBX2

  • Application

    SPRMSTBLIITCELISA细胞实验药物筛选

  • 别名

    LBX2; LP3727; Transcription factor LBX2; Ladybird homeobox protein homolog 2

  • 种属

    Human

  • 表达系统

    E. coli

  • 标签

    GST-tag at N-terminal

  • 纯度

    Greater than 90% as determined by SDS-PAGE.

  • 蛋白编号

    Q6XYB7

  • 表达区间

    1-194aa

  • 氨基酸序列

    MGKRTSLEVSLGELGGEKCRGGRRSFPPLAASRPARPGGWRWARRDLCKTASRAENNSQACRPQRRAGPDALGPGPFGRKRRKSRTAFTAQQVLELERRFVFQKYLAPSERDGLATRLGLANAQVVTWFQNRRAKLKRDVEEMRADVASLRALSPEVLCSLALPEGAPDPGLCLGPAGPDSRPHLSDEEIQVDD

  • 分子量

    47.8 kDa

  • 内毒素

    < 1.0 EU per μg protein as determined by the LAL method.

  • 性状

    Freeze-dried powder

  • 缓冲液

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • 复溶方法

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • 个性化定制

    点位突变 标签定制 buffer定制 全长蛋白定制

  • 稳定性测试

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • 保存条件 & 期限

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • 运输条件

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

LBX2 (LIM homeobox 2) is a transcription factor that belongs to the LIM-homeodomain family, characterized by a LIM domain that is critical for protein-protein interactions. This protein is primarily involved in the development of various tissues, including the nervous system and skeletal muscle. Dysfunction or abnormal expression of LBX2 has been implicated in various diseases, including cancers and developmental disorders. Studies have shown that LBX2 plays a pivotal role in neuronal differentiation and myogenesis, influencing cellular pathways that determine cell fate. The recombinant expression of LBX2 allows researchers to produce this protein in a controlled environment, facilitating the investigation of its functional roles and mechanisms. By using techniques such as molecular cloning and protein purification, scientists can analyze LBX2's interactions with other proteins and its regulatory effects on gene expression. This research has potential therapeutic implications, particularly in regenerative medicine and cancer treatment, where modulation of LBX2 activity could offer new strategies for intervention. Understanding the structure and function of LBX2 at a molecular level not only advances our knowledge of developmental biology but also opens avenues for exploring targeted therapies in related pathologies. Overall, the study of LBX2 recombinant protein is crucial for elucidating its contributions to cellular processes and disease mechanisms.

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IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
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