Analytical Data
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基因名
MOBKL1B
- Application
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别名
MOB1A;C2orf6;MOB4B;MOBK1B;MOB kinase activator 1A
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9H8S9
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表达区间
1-216aa
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氨基酸序列
MGSSHHHHHHSSGLVPRGSHMSFLFSSRSSKTFKPKKNIPEGSHQYELLK HAEATLGSGNLRQAVMLPEGEDLNEWIAVNTVDFFNQINMLYGTITEFCT EASCPVMSAGPRYEYHWADGTNIKKPIKCSAPKYIDYLMTWVQDQLDDET LFPSKIGVPFPKNFMSVAKTILKRLFRVYAHIYHQHFDSVMQLQEEAHLN TSFKHFIFFVQEFNLIDRRELAPLQELIEKLGSKDR
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分子量
27 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
MOBKL1B, or Mobo-like protein 1B, is part of the MOB family of proteins that play critical roles in various cellular processes, including cell cycle regulation, apoptosis, and signal transduction. The increasing interest in MOBKL1B is driven by its potential implications in cancer biology and cellular signaling pathways. Research has indicated that MOBKL1B may interact with key kinases, influencing cell proliferation and survival, making it a candidate for therapeutic interventions. Furthermore, alterations in its expression levels have been observed in several cancer types, suggesting a role in tumorigenesis and cancer progression. Studies have focused on the structural characterization and functional assays of MOBKL1B, including its binding partners and downstream effects on signaling cascades such as the Hippo pathway. Understanding the specific mechanisms by which MOBKL1B modulates these pathways could illuminate new avenues for targeted therapies and improve prognostic strategies in oncology. Continued exploration of MOBKL1B's roles in both normal and disease states remains crucial for deciphering its full biological significance and potential as a molecular target.
