Analytical Data
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基因名
MOB3B
- Application
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别名
MOB3B;C9orf35;MOBKL2B;MOB kinase activator 3B
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q86TA1
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表达区间
1-216aa
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氨基酸序列
MGSSHHHHHH SSGLVPRGSH MGSMSIALKQ VFNKDKTFRP KRKFEPGTQR FELHKRAQAS LNSGVDLKAA VQLPSGEDQN DWVAVHVVDF FNRINLIYGT ICEFCTERTC PVMSGGPKYE YRWQDDLKYK KPTALPAPQY MNLLMDWIEV QINNEEIFPT CVGVPFPKNF LQICKKILCR LFRVFVHVYI HHFDRVIVMG AEAHVNTCYK HFYYFVTEMN LIDRKELEPL KEMTSRMCH
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分子量
28 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
MOB3B is a member of the MOB family of proteins, which are implicated in various cellular processes, including cell division, signal transduction, and development. Research into MOB3B has gained attention due to its potential role in regulating the Hippo pathway, a critical signaling cascade that controls cell growth and proliferation, as well as tissue homeostasis. Dysregulation of this pathway is associated with several diseases, including cancer. Studies have shown that MOB3B interacts with specific kinases and regulatory proteins, influencing their activity and subsequent cellular responses. Moreover, recent investigations into the structure and function of MOB3B, including its post-translational modifications and interactions with other cellular components, have revealed insights into its role in modulating the Hippo pathway's activity. The recombinant expression of MOB3B allows for detailed functional studies, making it a valuable tool for dissecting the molecular mechanisms underlying its activity and contributions to health and disease. Overall, the exploration of MOB3B not only enhances our understanding of fundamental cellular processes but also holds potential for therapeutic applications in diseases driven by Hippo pathway dysregulation.
