Analytical Data
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Gene name
MOB3B
- Application
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Alternative Names
MOB3B;C9orf35;MOBKL2B;MOB kinase activator 3B
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q86TA1
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Expression Region
1-216aa
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AA Sequence
MGSSHHHHHH SSGLVPRGSH MGSMSIALKQ VFNKDKTFRP KRKFEPGTQR FELHKRAQAS LNSGVDLKAA VQLPSGEDQN DWVAVHVVDF FNRINLIYGT ICEFCTERTC PVMSGGPKYE YRWQDDLKYK KPTALPAPQY MNLLMDWIEV QINNEEIFPT CVGVPFPKNF LQICKKILCR LFRVFVHVYI HHFDRVIVMG AEAHVNTCYK HFYYFVTEMN LIDRKELEPL KEMTSRMCH
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Molecular Weight
28 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
MOB3B is a member of the MOB family of proteins, which are implicated in various cellular processes, including cell division, signal transduction, and development. Research into MOB3B has gained attention due to its potential role in regulating the Hippo pathway, a critical signaling cascade that controls cell growth and proliferation, as well as tissue homeostasis. Dysregulation of this pathway is associated with several diseases, including cancer. Studies have shown that MOB3B interacts with specific kinases and regulatory proteins, influencing their activity and subsequent cellular responses. Moreover, recent investigations into the structure and function of MOB3B, including its post-translational modifications and interactions with other cellular components, have revealed insights into its role in modulating the Hippo pathway's activity. The recombinant expression of MOB3B allows for detailed functional studies, making it a valuable tool for dissecting the molecular mechanisms underlying its activity and contributions to health and disease. Overall, the exploration of MOB3B not only enhances our understanding of fundamental cellular processes but also holds potential for therapeutic applications in diseases driven by Hippo pathway dysregulation.
