Cat: PA2000-4740

Recombinant Human LRRC17 Protein,His

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Analytical Data

  • Gene name

    LRRC17

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    LRRC17;P37NB;Leucine-rich repeat-containing Protein 17

  • Species

    Human

  • Source

    E. coli

  • Tag

    His tag N-Terminus

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    Q8N6Y2

  • Expression Region

    19-249aa

  • AA Sequence

    RKASPGSVRSRVNHGRAGGGRRGSNPVKRYAPGLPCDVYTYLHEKYLDCQERKLVYVLPGWPQDLLHMLLARNKIRTLKNNMFSKFKKLKSLDLQQNEISKIESEAFFGLNKLTTLLLQHNQIKVLTEEVFIYTPLLSYLRLYDNPWHCTCEIETLISMLQIPRNRNLGNYAKCESPQEQKNKKLRQIKSEQLCNEEEKEQLDPKPQVSGRPPVIKPEVDSTFCHNYVFPI

  • Molecular Weight

    42.2 kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

LRRC17 (Leucine-Rich Repeat Containing 17) is a protein that has garnered attention due to its potential role in various biological processes and diseases, including cancer and neurodegenerative disorders. This protein belongs to the leucine-rich repeat (LRR) family, which is characterized by the presence of multiple LRR motifs that are often involved in protein-protein interactions. Research has indicated that LRRC17 may play a critical role in cellular signaling pathways and immune responses, suggesting its importance in maintaining cellular homeostasis. Additionally, its expression patterns in different tissues and under various physiological conditions hint at its involvement in developmental processes. However, there is still a limited understanding of the functional mechanisms of LRRC17, as well as how its dysfunction might contribute to diseases. To address these gaps, studies on the recombinant form of LRRC17 have become essential for elucidating its structure-function relationships, interactions with other proteins, and potential implications in health and disease. Investigating the biochemical properties and physiological effects of recombinant LRRC17 will not only enhance our understanding of its biological significance but may also pave the way for developing therapeutic strategies targeting LRRC17-related pathways.

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