Analytical Data
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基因名
KRTAP6-1
- Application
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别名
KRTAP6-1; C21orf103; KAP6.1Keratin-associated protein 6-1
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q3LI64
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表达区间
1-71aa
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氨基酸序列
MCGSYYGNYYGTPGYGFCGYGGLGYGYGGLGCGYGSCCGCGFRRLGCGYGYGSRSLCGYGYGCGSGSGYYY
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分子量
34.21 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
KRTAP6-1, or Keratin Associated Protein 6-1, belongs to a family of keratin-associated proteins that play a crucial role in the structural integrity and functionality of hair and other keratinous tissues. The study of KRTAP6-1 is particularly relevant in the field of dermatology and genetics, as it is associated with the formation and maintenance of hair follicles and is implicated in various hair disorders. Research has shown that mutations or alterations in KRTAP genes can lead to hair abnormalities, such as hair loss or abnormal hair texture, making it a significant target for understanding the molecular mechanisms underlying these conditions. Moreover, KRTAP6-1's expression patterns and relationships with other keratins suggest its potential role in intercellular adhesion and skin barrier function. The recombinant production of KRTAP6-1 protein allows for the investigation of its biochemical properties and interactions at a molecular level, facilitating the development of therapeutic strategies for hair and skin disorders linked to keratin-associated protein dysfunction. Overall, the exploration of KRTAP6-1 and its functions provides valuable insights into keratin biology and its implications for dermatological health and hair follicle biology.
