Analytical Data
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基因名
METTL21A
- Application
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别名
METTL21A;FAM119A;HCA557B;Protein N-lysine methyltransferase METTL21A
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q8WXB1
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表达区间
93-218aa
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氨基酸序列
MGSSHHHHHH SSGLVPRGSH MGSTDRKVAL EFLKSNVQAN LPPHIQTKTV VKELTWGQNL GSFSPGEFDL ILGADIIYLE ETFTDLLQTL EHLCSNHSVI LLACRIRYER DNNFLAMLER QFTVRKVHYD PEKDVHIYEA QKRNQKEDL
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分子量
17 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
METTL21A, a member of the METTL (methyltransferase-like) family, has gained attention in recent years due to its potential roles in cellular processes and disease mechanisms. It is primarily recognized for its methyltransferase activity, which is believed to influence various biological processes, including RNA methylation and protein modifications. Dysregulation of METTL21A has been linked to several diseases, such as cancer and neurological disorders, suggesting its importance in maintaining cellular homeostasis. Research into METTL21A focuses on understanding its molecular mechanisms, regulatory pathways, and its interactions with other biomolecules. Additionally, the exploration of METTL21A as a therapeutic target has garnered interest, as modulating its activity could have implications for treating diseases associated with its dysfunction. Furthermore, studies utilizing recombinant METTL21A protein aim to elucidate its specific role in methylation dynamics and its functional impact on gene expression and cellular signaling pathways. Overall, the investigation of METTL21A represents a critical frontier in epitranscriptomics and molecular biology, with the potential to unveil novel insights into gene regulation and the etiology of various diseases.
