Analytical Data
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Gene name
KRTAP19-6
- Application
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Alternative Names
KRTAP19-6; KAP19.6Keratin-associated protein 19-6
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Species
Human
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Source
E. coli
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Tag
GST-tag at N-terminal
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q3LI70
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Expression Region
1-58aa
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AA Sequence
MRYYGSYYRGLGYGCGGFGGLGYGCGCGGYRYGSGYGGYRYGCCRPSCREGYGFSGFY
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Molecular Weight
32.78 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
KRTAP19-6, a member of the keratin-associated protein (KRTAP) family, plays a crucial role in the formation and structural integrity of hair and skin. Researchers are particularly interested in this protein due to its unique expression patterns and potential implications in dermatological and genetic disorders. KRTAPs contribute to the biophysical properties of hair fibers, such as strength and elasticity, making them essential for understanding hair follicle biology. Mutations or dysregulation of KRTAP genes can lead to various hair and skin conditions, including hair loss, alopecia, and other keratinization disorders. Recombinant KRTAP19-6 protein has been produced for investigation into its functional properties and interactions within the keratinocyte environment. By studying the structural and biochemical characteristics of KRTAP19-6, researchers aim to elucidate its role in keratinization and explore its potential as a therapeutic target for treating hair and skin diseases. Furthermore, understanding the molecular mechanisms underlying KRTAP19-6's function may provide insights into the evolutionary adaptations of hair and skin in different mammalian species. As research progresses, KRTAP19-6 stands out as a significant focal point within the broader context of dermatological sciences, offering potential pathways for innovative treatments and advancements in hair care and regenerative medicine.
