Analytical Data
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Gene name
MAPK9
- Application
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Alternative Names
MAPK9;JNK2;PRKM9;SAPK1A;Mitogen-activated Protein kinase 9
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P45984
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Expression Region
1-424aa
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AA Sequence
MSDSKCDSQFYSVQVADSTFTVLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRPFQNQTHAKRAYRELVLLKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIHMELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTACTNFMMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGELVKGCVIFQGTDHIDQWNKVIEQLGTPSAEFMKKLQPTVRNYVENRPKYPGIKFEELFPDWIFPSESERDKIKTSQARDLLSKMLVIDPDKRISVDEALRHPYITVWYDPAEAEAPPPQIYDAQLEEREHAIEEWKELIYKEVMDWEERSKNGVVKDQPSDAAVSSNATPSQSSSINDISSMSTEQTLASDTDSSLDASTGPLEGCR
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Molecular Weight
64.1kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
MAPK9, also known as c-Jun N-terminal kinase 2 (JNK2), is a member of the mitogen-activated protein kinase (MAPK) family, which plays a critical role in various cellular processes, including stress responses, apoptosis, and differentiation. The MAPK signaling pathway is highly conserved and is activated by various extracellular stimuli, leading to diverse intracellular responses that ultimately modulate gene expression. MAPK9 specifically regulates a range of physiological and pathological processes, such as inflammatory responses, neuronal function, and tumorigenesis. Due to its involvement in multiple diseases, including cancer and neurodegenerative disorders, there is a growing interest in understanding the structure, function, and regulation of MAPK9. Recombinant MAPK9 protein production allows researchers to investigate its biochemical properties, phosphorylation status, and interaction with other signaling molecules. The ability to study MAPK9 in a controlled experimental environment enhances our understanding of its mechanisms and potential therapeutic targets. Furthermore, the development of MAPK9 inhibitors could offer new avenues for treating diseases linked to its dysregulation. Overall, the study of recombinant MAPK9 not only elucidates its biological functions but also provides significant insights into developing novel therapeutic strategies for diseases where this kinase plays a crucial role.
