Analytical Data
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基因名
KLF7
- Application
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别名
KLF7; KLF7_HUMAN; Krueppel like factor 7; Krueppel-like factor 7; Kruppel like factor 7; Ubiquitous krueppel like factor ; Ubiquitous krueppel-like factor; UKLF
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
O75840
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表达区间
1-302aa
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氨基酸序列
MDVLASYSIF QELQLVHDTG YFSALPSLEE TWQQTCLELE RYLQTEPRRI SETFGEDLDC FLHASPPPCI EESFRRLDPL LLPVEAAICE KSSAVDILLS RDKLLSETCL SLQPASSSLD SYTAVNQAQL NAVTSLTPPS SPELSRHLVK TSQTLSAVDG TVTLKLVAKK AALSSVKVGG VATAAAAVTA AGAVKSGQSD SDQGGLGAEA CPENKKRVHR CQFNGCRKVY TKSSHLKAHQ RTHTGEKPYK CSWEGCEWRF ARSDELTRHY RKHTGAKPFK CNHCDRCFSR SDHLALHMKR HI
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分子量
33.3 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
KLF7, or Krüppel-like factor 7, is a member of the Krüppel-like factor family of transcription factors, playing significant roles in various biological processes such as cell differentiation, proliferation, and metabolism. The dysregulation of KLF7 has been implicated in several diseases, including diabetes, cardiovascular disorders, and cancer, making it a critical target for research. Recent studies have shown that KLF7 is involved in regulating insulin signaling and β-cell function, highlighting its potential in diabetes therapy. Additionally, KLF7's role in adipogenesis and muscle differentiation suggests its importance in metabolic regulation and body composition. The expression and activity of KLF7 can be influenced by various signaling pathways, including those mediated by growth factors and hormones, which underscores the complexity of its regulatory mechanisms. Research into recombinant KLF7 protein focuses on its structure-function relationship and biological activities, facilitating the understanding of its mechanisms and interactions at the molecular level. By studying KLF7 in a recombinant system, scientists aim to unravel its therapeutic potential, elucidate its role in metabolic diseases, and explore its applicability as a biomarker or target for interventions. The production of recombinant KLF7 not only provides a tool for further functional studies but also enhances the potential for designing novel therapeutic strategies that can modulate its activity in disease contexts. Through the comprehensive exploration of KLF7's biological significance and therapeutic relevance, this field holds promise for advancing our understanding of metabolic diseases and developing innovative treatments.












