Cat: PA2000-8732

Recombinant Human KLF16 Protein,GST

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Analytical Data

  • Gene name

    KLF16

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    AI843742; Basic transcription element binding protein 4; Basic transcription element-binding protein 4; BTE binding protein 4; BTE-binding protein 4; BTEB 4; BTEB4; Dopamine receptor regulating factor; DRRF; KLF 16; Klf16; KLF16_HUMAN; Krueppel-like factor 16; Kruppel like factor 16; Likely ortholog of mouse dopamine receptor regulating factor; MGC187751; Novel Sp1 like zinc finger transcription factor 2; Novel Sp1-like zinc finger transcription factor 2

  • Species

    Human

  • Source

    E. coli

  • Tag

    GST-tag at N-terminal

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    Q9BXK1

  • Expression Region

    1-252aa

  • AA Sequence

    MSAAVACVDYFAADVLMAISSGAVVHRGRPGPEGAGPAAGLDVRAARREAASPGTPGPPPPPPAASGPGPGAAAAPHLLAASILADLRGGPGAAPGGASPASSSSAASSPSSGRAPGAAPSAAAKSHRCPFPDCAKAYYKSSHLKSHLRTHTGERPFACDWQGCDKKFARSDELARHHRTHTGEKRFSCPLCSKRFTRSDHLAKHARRHPGFHPDLLRRPGARSTSPSDSLPCSLAGSPAPSPAPSPAPAGL

  • Molecular Weight

    54.67 kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

Quality inspection process

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Protein Description

KLF16, a member of the Kruppel-like factor (KLF) family of transcription factors, plays a crucial role in various biological processes, including cell differentiation, proliferation, and apoptosis. Recent studies have highlighted its potential involvement in regulating gene expression associated with cardiovascular diseases, metabolic disorders, and cancer. The reconstitution of KLF16 as a recombinant protein has emerged as a key strategy for elucidating its functional mechanisms in cellular pathways. By producing KLF16 in a recombinant form, researchers can investigate its regulatory effects on target genes and interact with other signaling molecules in vitro. Furthermore, recombinant KLF16 can be used to explore its role in tissue-specific functions and developmental processes, contributing to a greater understanding of its physiological significance. This research highlights the importance of KLF16 in maintaining cellular homeostasis and its potential as a therapeutic target for various diseases. The continued investigation of KLF16 through recombinant protein studies is expected to provide valuable insights into the molecular underpinnings of its actions and pave the way for novel therapeutic strategies aimed at mitigating the associated pathologies.


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