Analytical Data
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基因名
XCL1
- Application
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别名
XCL1;LTN;SCYC1;Lymphotactin
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P47992
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表达区间
23-114aa
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氨基酸序列
GSEVSDKRTC VSLTTQRLPV SRIKTYTITE GSLRAVIFIT KRGLKVCADP QATWVRDVVR SMDRKSNTRN NMIQTKPTGT QQSTNTAVTL TG
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分子量
10.2 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
XCL1, or X-C motif chemokine ligand 1, is a cytokine belonging to the CC chemokine family, playing a critical role in immune responses by attracting T cells and dendritic cells to sites of inflammation. Its significance has garnered attention in various fields of biomedical research, particularly in cancer immunology and autoimmune diseases. Recent studies have highlighted the potential of XCL1 as a therapeutic target due to its involvement in tumor microenvironments and its ability to modulate immune responses. Researchers have focused on the production and characterization of recombinant XCL1 protein to better understand its biological functions and mechanisms. This recombinant protein facilitates in vitro studies, allowing for the examination of XCL1's interactions with its receptor, XCR1, and its effects on immune cell recruitment and activation. Furthermore, understanding the structure-function relationship of XCL1 through recombinant variants could lead to novel therapies enhancing anti-tumor immunity or alleviating autoimmune disorders. Given the increasing evidence of XCL1's critical role in shaping immune responses, ongoing research aims to elucidate its potential as a biomarker for disease prognosis and treatment response, showcasing the importance of XCL1 recombinant protein in advancing therapeutic strategies in immuno-oncology.












