Analytical Data
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基因名
KIF11
- Application
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别名
EG5; HKSP; KIF11; KIF11_HUMAN; Kinesin family member 11; Kinesin like protein 1; Kinesin-like protein 1; Kinesin-like protein KIF11; Kinesin-like spindle protein HKSP; Kinesin-related motor protein Eg5; KNSL1; MCLMR; Thyroid receptor-interacting protein 5
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P52732
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表达区间
947-1056aa
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氨基酸序列
LLDQLKRKQPELLMMLNCSENNKEETIPDVDVEEAVLGQYTEEPLSQEPSVDAGVDCSSIGGVPFFQHKKSHGKDKENRGINTLERSKVEETTEHLVTKSRLPLRAQINL
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分子量
37.84 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
KIF11, also known as kinesin family member 11, is a molecular motor protein that plays a crucial role in intracellular transport and mitotic spindle dynamics during cell division. As a member of the kinesin superfamily, KIF11 is involved in the transport of various cellular cargoes, including organelles and protein complexes, along microtubules. Its significance has drawn attention in cancer research, as aberrant expression or mutations in KIF11 can lead to dysregulated cellular processes and contribute to tumorigenesis. The study of KIF11 recombinant proteins has become increasingly relevant for understanding its functional mechanisms and potential as a therapeutic target. By producing and analyzing recombinant KIF11 proteins, researchers aim to elucidate the specific roles of this motor protein in cellular logistics and its interaction with microtubules. Such studies may provide insights into the molecular pathways underlying cancer progression and offer avenues for the development of novel anticancer strategies, highlighting KIF11 as a promising candidate for targeted therapies.
