Analytical Data
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基因名
JDP2
- Application
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别名
JDP2;Jun dimerization Protein 2
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q8WYK2
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表达区间
1-163aa
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氨基酸序列
MGSSHHHHHH SSGLVPRGSH MGSHMMPGQI PDPSVTTGSL PGLGPLTGLP SSALTVEELK YADIRNLGAM IAPLHFLEVK LGKRPQPVKS ELDEEEERRK RRREKNKVAA ARCRNKKKER TEFLQRESER LELMNAELKT QIEELKQERQ QLILMLNRHR PTCIVRTDSV KTPESEGNPL LEQLEKK
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分子量
21 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
JDP2 (Jun dimerization protein 2) is a member of the AP-1 family of transcription factors, playing a pivotal role in various biological processes, including cellular differentiation, proliferation, and apoptosis. Research has increasingly focused on JDP2 due to its potential involvement in pathophysiological conditions, such as cancer and cardiovascular diseases. JDP2 acts as a transcriptional repressor, modulating the activity of other AP-1 proteins by interacting with them and influencing the expression of target genes. This interaction is vital for maintaining cellular homeostasis and response to environmental stimuli. Moreover, JDP2 has been implicated in the regulation of inflammatory responses and oxidative stress, further underscoring its significance in health and disease. Understanding the molecular mechanisms underlying JDP2 action can illuminate its role in these processes and may provide novel therapeutic targets for related disorders. Researchers are employing various techniques, including protein overexpression, gene knockdown, and structural analysis, to investigate the functional properties of JDP2 and its interactions within the broader AP-1 framework. This research aims to clarify JDP2's specific roles in signaling pathways and its potential as a biomarker or therapeutic target, reflecting the importance of transcriptional regulation in cellular dynamics and disease progression.












