Analytical Data
-
基因名
KCNV1
- Application
-
别名
KCNV1; Potassium voltage-gated channel subfamily V member 1; Neuronal potassium channel alpha subunit HNKA; Voltage-gated potassium channel subunit Kv8.1
-
种属
Human
-
表达系统
E. coli
-
标签
GST-tag at N-terminal
-
纯度
Greater than 90% as determined by SDS-PAGE.
-
蛋白编号
Q6PIU1
-
表达区间
1-500aa
-
氨基酸序列
MPSSGRALLDSPLDSGSLTSLGSSVFCSEGEGEPLALGDCFTVNVGGSRFVLSQQALSCFPHTRLGKLAVVVASYRRPGALAAVPSPLELCDDANPVDNEYFFDRSSQAFRYVLHYYRTGRLHVMEQLCALSFLQEIQYWGIDELSIDSCCRDRYFRRKELSETLDFKKDTEDQESQHESEQDFSQGPCPTVRQKLWNILEKPGSSTAARIFGVISIIFVVVSIINMALMSAELSWLDLQLLEILEYVCISWFTGEFVLRFLCVRDRCRFLRKVPNIIDLLAILPFYITLLVESLSGSQTTQELENVGRIVQVLRLLRALRMLKLGRHSTGLRSLGMTITQCYEEVGLLLLFLSVGISIFSTVEYFAEQSIPDTTFTSVPCAWWWATTSMTTVGYGDIRPDTTTGKIVAFMCILSGILVLALPIAIINDRFSACYFTLKLKEAAVRQREALKKLTKNIATDSYISVNLRDVYARSIMEMLRLKGRERASTRSSGGDDFWF
-
分子量
82.6 kDa
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
-
性状
Freeze-dried powder
-
缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
-
稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
KCNV1, a member of the potassium channel family, encodes a voltage-gated potassium ion channel that plays a critical role in maintaining the membrane potential and regulating neuronal excitability. Research into KCNV1 has gained momentum in recent years due to its involvement in various pathological conditions, including epilepsy and other neurological disorders. The dysfunction of this channel can lead to altered neuronal firing patterns and ultimately contribute to the symptoms associated with these diseases. The recombinant expression of KCNV1 protein allows for detailed biophysical studies and functional assays, which are essential for understanding its precise mechanisms of action. By utilizing techniques such as X-ray crystallography and electrophysiology, researchers can investigate the structural and functional properties of KCNV1, paving the way for potential therapeutic interventions. Furthermore, the development of KCNV1-targeted drugs could provide novel treatment options for patients suffering from channelopathies. As such, the study of KCNV1 recombinant protein is not only vital for the elucidation of its biological functions but also for facilitating the discovery of innovative pharmacological strategies to combat associated neurological disorders.
