Analytical Data
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Gene name
KCNRG
- Application
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Alternative Names
KCNRG; CLLD4Potassium channel regulatory protein; Potassium channel regulator; Protein CLLD4
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Species
Human
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Source
E. coli
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Tag
GST-tag at N-terminal
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q8N5I3
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Expression Region
1-272aa
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AA Sequence
MSSQELVTLNVGGKIFTTRFSTIKQFPASRLARMLDGRDQEFKMVGGQIFVDRDGDLFSFILDFLRTHQLLLPTEFSDYLRLQREALFYELRSLVDLLNPYLLQPRPALVEVHFLSRNTQAFFRVFGSCSKTIEMLTGRITVFTEQPSAPTWNGNFFPPQMTLLPLPPQRPSYHDLVFQCGSDSTTDNQTGVRYVSIKPDNRKLANGTNVLGLLIDTLLKEGFHLVSTRTVSSEDKTECYSFERIKSPEVLITNETPKPETIIIPEQSQIKK
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Molecular Weight
57.4 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
KCNRG (KC neurite outgrowth regulator) is a protein that has garnered attention in the field of neuroscience due to its potential role in neuronal development and function. Initially identified based on its ability to regulate neurite outgrowth, KCNRG is believed to influence neural circuitry and synaptic plasticity, both of which are vital for cognitive processes and memory formation. Recent studies have suggested that abnormalities in KCNRG expression may be linked to various neurodevelopmental and neurodegenerative disorders, prompting researchers to investigate its molecular mechanisms and interactions with other proteins. Additionally, the recombinant production of KCNRG has enabled detailed studies of its structure and function, facilitating the exploration of its role in neuronal health and disease. The ongoing research aims to elucidate KCNRG's contributions to neural network formation, providing insights that could pave the way for novel therapeutic strategies targeting cognitive impairments and neurodegenerative conditions. Understanding KCNRG's functions at a molecular level could not only advance our knowledge of neurobiology but also offer potential biomarkers for early diagnosis and treatment in related disorders.
