Analytical Data
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Gene name
IPP-POZ
- Application
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Alternative Names
KLHL21;KIAA0469;Kelch-like Protein 21
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P49441
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Expression Region
1-399aa
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AA Sequence
MSDILRELLC VSEKAANIAR ACRQQEALFQ LLIEEKKEGE KNKKFAVDFK TLADVLVQEV IKQNMENKFP GLEKNIFGEE SNEFTNDWGE KITLRLCSTE EETAELLSKV LNGNKVASEA LARVVHQDVA FTDPTLDSTE INVPQDILGI WVDPIDSTYQ YIKGSADIKS NQGIFPCGLQ CVTILIGVYD IQTGVPLMGV INQPFVSRDP NTLRWKGQCY WGLSYMGTNM HSLQLTISRR NGSETHTGNT GSEAAFSPSF SAVISTSEKE TIKAALSRVC GDRIFGAAGA GYKSLCVVQG LVDIYIFSED TTFKWDSCAA HAILRAMGGG IVDLKECLER NPETGLDLPQ LVYHVENEGA AGVDRWANKG GLIAYRSRKR LETFLSLLVQ NLAPAETHT
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
The research on IPP-POZ recombinant proteins has gained significant attention due to their potential roles in various biological processes and therapeutic applications. IPP (Inhibitor of Apoptosis Protein) is known for its involvement in regulating apoptosis, cell proliferation, and response to stress, while the POZ (Poxvirus and Zinc-finger) domain is associated with protein-protein interactions and has crucial functions in transcriptional regulation. Understanding the structure and function of IPP-POZ proteins can provide insights into the mechanisms underlying cellular survival and death, making them important targets in cancer research and drug development. Additionally, the manipulation of these proteins through recombinant technologies can pave the way for novel therapeutic strategies, such as enhancing apoptosis in cancer cells or designing targeted therapies for diseases linked to dysregulation of apoptosis. By elucidating the molecular pathways involving IPP-POZ proteins, researchers aim to contribute to the development of effective treatments for a range of conditions, including cancer, autoimmune disorders, and neurodegenerative diseases. Thus, the exploration of IPP-POZ recombinant proteins stands at the forefront of molecular biology and therapeutic innovation, highlighting the importance of such studies in advancing our understanding of complex biological systems.
