Cat: PA1000-1662

Recombinant Human IFNA2 Protein,His

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Analytical Data

  • 基因名

    IFNA2

  • Application

    SPRMSTBLIITCELISA细胞实验药物筛选

  • 别名

    IFNA2;IFNA2A;IFNA2B;IFNA2C;Interferon alpha-2

  • 种属

    Human

  • 表达系统

    E. coli

  • 标签

    His tag N-Terminus

  • 纯度

    Greater than 90% as determined by SDS-PAGE.

  • 蛋白编号

    P01563

  • 表达区间

    24-188aa

  • 氨基酸序列

    MFCDLPQTHSLGSRRTLMLLAQMRRISLFSCLKDRHDFGFPQEEFGNQFQ KAETIPVLHEMIQQIFNLFSTKDSSAAWDETLLDKFYTELYQQLNDLEAC VIQGVGVTETPLMKEDSILAVRKYFQRITLYLKEKKYSPCAWEVVRAEIM RSFSLSTNLQESLRSKE

  • 分子量

    20 kDa

  • 内毒素

    < 1.0 EU per μg protein as determined by the LAL method.

  • 性状

    Freeze-dried powder

  • 缓冲液

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • 复溶方法

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • 个性化定制

    点位突变 标签定制 buffer定制 全长蛋白定制

  • 稳定性测试

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • 保存条件 & 期限

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • 运输条件

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

IFNA2, a subtype of interferon alpha, plays a crucial role in the body's immune response against viral infections and tumor growth. Its therapeutic potential has long been recognized, particularly in the treatment of various cancers and viral diseases such as hepatitis C. Given its pivotal role in mediating antiviral effects, researchers have focused on the recombinant production of IFNA2 to enhance its availability and efficacy for clinical applications. Advances in biotechnology, particularly in recombinant DNA technology, have facilitated the efficient expression and purification of IFNA2 in host systems such as bacteria, yeast, and mammalian cells. This recombinant protein not only replicates the biological activities of native IFNA2 but also allows for modifications to improve its stability and therapeutic potency. The understanding of its mechanism of action has further propelled research into its use in combination therapies, especially in oncology, where it can augment the effects of other anticancer agents. Continued investigation into IFNA2's immune-modulating properties, coupled with emerging platform technologies for its production, holds promise for the development of innovative therapeutics to combat persistent viral infections and malignancies. Ultimately, the ongoing studies aim to optimize the efficacy and safety profiles of IFNA2-based therapies, thereby expanding their use in clinical settings and improving patient outcomes.

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IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
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