Analytical Data
-
基因名
TRPM6
- Application
-
别名
TRPM6；CHAK2；Transient receptor potential cation channel subfamily M member 6
-
种属
Human
-
表达系统
E. coli
-
标签
His tag N-Terminus
-
纯度
Greater than 90% as determined by SDS-PAGE.
-
蛋白编号
Q9BX84
-
表达区间
全长
-
氨基酸序列
full
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
-
性状
Freeze-dried powder
-
缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
-
稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
TRPM6 (Transient Receptor Potential Melastatin 6) is a member of the TRP channel family and plays a critical role in magnesium homeostasis, which is essential for various physiological processes. Its dysfunction is associated with conditions like hypomagnesemia and related diseases. Recent studies have highlighted the importance of TRPM6 in cellular magnesium uptake and its influence on cellular signaling pathways. The reconstitution of TRPM6 in various experimental models, including heterologous systems, allows researchers to dissect its functional properties and regulatory mechanisms. Understanding TRPM6’s structure and function through recombinant protein studies can provide insights into its role in health and disease, paving the way for potential therapeutic interventions targeting magnesium metabolism disorders. Through these investigations, scientists aim to elucidate the mechanistic basis of TRPM6 channel activity, its interaction with other cellular components, and its contribution to overall mineral balance in the body.
