Analytical Data
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基因名
MIA
- Application
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别名
MIA；Melanoma-derived growth regulatory Protein
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q16674
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表达区间
25-131aa
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氨基酸序列
GPMPKLADRK LCADQECSHP ISMAVALQDY MAPDCRFLTI HRGQVVYVFS KLKGRGRLFW GGSVQGDYYG DLAARLGYFP SSIVREDQTL KPGKVDVKTD KWDFYCQ
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分子量
12.1 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
MIA (Melanoma Inhibitory Activity) is a pivotal protein initially identified for its role in melanoma cell biology. Its expression has been linked to tumor progression and metastasis, making it a subject of intense study in cancer research. MIA is known to influence cell adhesion, migration, and interaction with the extracellular matrix, contributing to the aggressive nature of melanoma. Beyond melanoma, its expression has been observed in various other malignancies, suggesting a broader role in oncogenic processes. The reconstitution of MIA in research settings enables the exploration of its structural and functional characteristics, revealing insights into its mechanisms of action. This includes its potential as a biomarker for diagnosis and prognosis in cancer patients. Additionally, recombinant MIA proteins can be utilized in therapeutic contexts, where they may assist in the development of targeted treatments. The ongoing investigation of MIA not only enhances our understanding of melanoma biology but also underscores the importance of protein interactions in cancer progression and metastasis.
