Analytical Data
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基因名
CACNa1D
- Application
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别名
CACNa1D；CACH3；CACN4；CACNL1A2；Voltage-dependent L-type calcium channel subunit alpha-1D
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q01668
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表达区间
全长
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氨基酸序列
full
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
The CACNa1D gene encodes the alpha-1D subunit of voltage-gated calcium channels, which are essential for a wide range of physiological processes, including muscle contraction, neurotransmitter release, and signal transduction in neurons. Dysregulation or mutations in CACNa1D have been linked to various cardiovascular diseases, neurological disorders, and other health issues. Research into CACNa1D recombinant proteins has gained momentum, as these proteins serve as valuable tools for studying the structure-function relationships of calcium channels, understanding their role in disease mechanisms, and developing therapeutic interventions. By producing CACNa1D in heterologous expression systems, researchers can obtain sufficient quantities of the protein for in vitro studies, allowing for detailed investigations into its biophysical properties, pharmacological profiles, and interactions with other cellular components. The study of CACNa1D recombinant proteins contributes not only to the fundamental understanding of calcium signaling but also to the potential development of targeted therapies for disorders associated with calcium channel dysfunction. Thus, the exploration of this important protein has significant implications for both basic science and clinical applications.
