Analytical Data
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基因名
KAL
- Application
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别名
KAL；KLK3；Plasma kallikrein
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P23352
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表达区间
384-680aa
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氨基酸序列
RLKSAKVSLH FTSTHATNNK EQLVKTRKGG IQTQLPFQRR RPTRPLEVGA PFYQDGQLQV KVYWKKTEDP TVNRYHVRWF PEACAHNRTT GSEASSGMTH ENYIILQDLS FSCKYKVTVQ PIRPKSHSKA EAVFFTTPPC SALKGKSHKP VGCLGEAGHV LSKVLAKPEN LSASFIVQDV NITGHFSWKM AKANLYQPMT GFQVTWAEVT TESRQNSLPN SIISQSQILP SDHYVLTVPN LRPSTLYRLE VQVLTPGGEG PATIKTFRTP ELPPSSAHRS HLKHRHPHHY KPSPERY
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分子量
36 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
KAL, or Kallmann syndrome protein, is a crucial component in the understanding of various genetic and developmental disorders. It primarily encodes a protein involved in the migration of gonadotropin-releasing hormone (GnRH) neurons during embryonic development. Mutations in the KAL gene are linked to Kallmann syndrome, a genetic condition characterized by delayed or absent puberty and a reduced sense of smell due to the improper formation and function of the reproductive system. Research into KAL recombinant proteins aims to elucidate the mechanisms of GnRH neuronal migration and function, providing insights into the pathology of Kallmann syndrome and related disorders. Additionally, studying the structure and function of the KAL protein may open new avenues for therapeutic interventions and enhance our understanding of reproductive endocrinology. Understanding the role of KAL can also shed light on broader neurodevelopmental processes, as similar mechanisms may be involved in other neurological and hormonal systems. Thus, the investigation of KAL recombinant proteins not only holds potential for addressing specific genetic disorders but also contributes to the overall knowledge of human development and neurobiology.
