Cat: PA2000-4355

Recombinant Human D266N Protein,His

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Analytical Data

  • 基因名

    D266N

  • Application

    SPRMSTBLIITCELISA细胞实验药物筛选

  • 别名

    D266N;

  • 种属

    Human

  • 表达系统

    E. coli

  • 标签

    His tag N-Terminus

  • 纯度

    Greater than 90% as determined by SDS-PAGE.

  • 蛋白编号

    P30530

  • 表达区间

    26-451aa

  • 氨基酸序列

    APRGTQAEESPFVGNPGNITGARGLTGTLRCQLQVQGEPPEVHWLRDGQILELADSTQTQVPLGEDEQDDWIVVSQLRITSLQLSDTGQYQCLVFLGHQTFVSQPGYVGLEGLPYFLEEPEDRTVAANTPFNLSCQAQGPPEPVDLLWLQDAVPLATAPGHGPQRSLHVPGLNKTSSFSCEAHNAKGVTTSRTATITVLPQQPRNLHLVSRQPTELEVAWTPGLSGIYPLTHCTLQAVLSNDGMGIQAGEPDPPEEPLTSQASVPPHQLRLGSLHPHTPYHIRVACTSSQGPSSWTHWLPVETPEGVPLGPPENISATRNGSQAFVHWQEPRAPLQGTLLGYRLAYQGQDTPEVLMDIGLRQEVTLELQGDGSVSNLTVCVAAYTAAGDGPWSLPVPLEAWRPGQAQPVHQLVKEPSTPAFSWPWW

  • 分子量

    75.1 kDa

  • 内毒素

    < 1.0 EU per μg protein as determined by the LAL method.

  • 性状

    Freeze-dried powder

  • 缓冲液

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • 复溶方法

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • 个性化定制

    点位突变 标签定制 buffer定制 全长蛋白定制

  • 稳定性测试

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • 保存条件 & 期限

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • 运输条件

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

The D266N recombinant protein has garnered attention in the fields of molecular biology and biochemistry due to its potential implications in understanding disease mechanisms and therapeutic development. This protein variant is a specific mutation in the gene encoding for a target enzyme or receptor, which is often linked to various pathological conditions. Research into the D266N mutation aims to unravel its effects on protein structure, function, and stability, as mutations in critical residues can lead to altered enzymatic activity or disrupted interactions with other biomolecules. Such studies are crucial for elucidating the biological roles of this protein and its involvement in metabolic pathways or signaling cascades. Additionally, the recombinant expression of D266N allows for the investigation of its properties in vitro, enabling researchers to assess how this specific alteration can influence drug binding or the efficacy of therapeutic agents. Understanding the functional consequences of the D266N mutation can contribute to the development of targeted treatments, personalized medicine approaches, and the discovery of biomarkers for disease diagnosis and prognosis. Furthermore, the study of this recombinant protein can provide insights into broader biological processes, highlighting the importance of protein engineering and molecular characterization in modern biomedical research. As the search for innovative solutions to complex diseases continues, the D266N recombinant protein serves as a valuable model for exploring the intricate relationships between genetic variations and pathophysiological outcomes.

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IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
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