Analytical Data
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基因名
HSPB7
- Application
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别名
HSPB7;CVHSP;Heat shock Protein beta-7
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9UBY9
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表达区间
1-170aa
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氨基酸序列
MSHRTSSTFRAERSFHSSSSSSSSSTSSSASRALPAQDPPMEKALSMFSD DFGSFMRPHSEPLAFPARPGGAGNIKTLGDAYEFAVDVRDFSPEDIIVTT SNNHIEVRAEKLAADGTVMNTFAHKCQLPEDVDPTSVTSALREDGSLTIR ARRHPHTEHVQQTFRTEIKILEHHHHHH
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分子量
19 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
HSPB7, a member of the small heat shock protein (sHSP) family, has garnered significant research interest due to its potential protective roles in cellular stress responses, particularly in the context of cardiovascular diseases. Emerging evidence suggests that HSPB7 plays a crucial role in maintaining proteostasis, protecting cells from apoptosis, and modulating inflammation. Its expression is upregulated in response to various stressors, including oxidative stress and ischemia, highlighting its importance in cellular defense mechanisms. Dysregulation of HSPB7 has been linked to various pathological conditions, including heart failure and cardiomyopathies, making it a compelling target for therapeutic intervention. Recent studies have focused on the recombinant production of HSPB7 to better understand its functional properties and interactions with other cellular proteins. This approach not only facilitates the elucidation of its molecular mechanisms but also opens avenues for developing HSPB7-based therapies aimed at enhancing cardioprotection. As a result, investigating HSPB7 through recombinant protein techniques is pivotal for advancing our understanding of cardiovascular health and disease, paving the way for innovative treatment strategies.
