Analytical Data
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基因名
Nav3
- Application
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别名
Nav3；KIAA0938；POMFIL1；STEERIN3；Neuron navigator 3
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q8IVL0
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表达区间
全长
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氨基酸序列
full
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
Nav3, or Neuronal Activity Regulated Protein 3, is a member of the neuronal activity-regulated gene family that plays a critical role in neuronal development and synaptic plasticity. Research into Nav3 and its recombinant protein has garnered interest due to its potential implications in neurobiology and neurodegenerative diseases. The protein is believed to be involved in the modulation of neurotransmitter release and in the structural changes of synapses in response to neuronal activity. Understanding the molecular mechanisms underlying Nav3’s function can provide insights into its role in learning, memory, and the pathophysiology of conditions such as Alzheimer's disease, schizophrenia, and depression. Recombinant Nav3 proteins are being explored for their potential as therapeutic targets or biomarkers, emphasizing the need for in-depth biochemical characterization and analysis. Current studies aim to elucidate the receptor interactions and signaling pathways influenced by Nav3, utilizing advanced techniques in molecular biology and protein engineering to generate functional recombinant Nav3 proteins. This research not only advances our understanding of synaptic dynamics but also lays the groundwork for developing novel strategies in treating synaptic dysfunctions associated with various neurological disorders.
