Analytical Data
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Gene name
Nav3
- Application
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Alternative Names
Nav3；KIAA0938；POMFIL1；STEERIN3；Neuron navigator 3
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q8IVL0
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Expression Region
全长
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AA Sequence
full
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
Nav3, or Neuronal Activity Regulated Protein 3, is a member of the neuronal activity-regulated gene family that plays a critical role in neuronal development and synaptic plasticity. Research into Nav3 and its recombinant protein has garnered interest due to its potential implications in neurobiology and neurodegenerative diseases. The protein is believed to be involved in the modulation of neurotransmitter release and in the structural changes of synapses in response to neuronal activity. Understanding the molecular mechanisms underlying Nav3’s function can provide insights into its role in learning, memory, and the pathophysiology of conditions such as Alzheimer's disease, schizophrenia, and depression. Recombinant Nav3 proteins are being explored for their potential as therapeutic targets or biomarkers, emphasizing the need for in-depth biochemical characterization and analysis. Current studies aim to elucidate the receptor interactions and signaling pathways influenced by Nav3, utilizing advanced techniques in molecular biology and protein engineering to generate functional recombinant Nav3 proteins. This research not only advances our understanding of synaptic dynamics but also lays the groundwork for developing novel strategies in treating synaptic dysfunctions associated with various neurological disorders.
