Analytical Data
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基因名
IMMP1L
- Application
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别名
IMMP1LMitochondrial inner membrane protease subunit 1; EC 3.4.21.-; IMP1-like protein
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q96LU5
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表达区间
1-166aa
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氨基酸序列
MLRGVLGKTFRLVGYTIQYGCIAHCAFEYVGGVVMCSGPSMEPTIQNSDIVFAENLSRHFYGIQRGDIVIAKSPSDPKSNICKRVIGLEGDKILTTSPSDFFKSHSYVPMGHVWLEGDNLQNSTDSRCYGPIPYGLIRGRIFFKIWPLSDFGFLRASPNGHRFSDD
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分子量
44.9 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
IMMP1L (Inner Mitochondrial Membrane Protease 1 Like) is a mitochondrial enzyme that plays a crucial role in protein quality control within the mitochondria, an organelle essential for energy production and cellular metabolism. Recent studies have established that IMMP1L is involved in the processing and degradation of mitochondrial precursor proteins, which is vital for maintaining mitochondrial function and integrity. Given its significance, dysregulation of IMMP1L has been implicated in various mitochondrial disorders and has potential links to age-related diseases. Research focusing on the recombinant expression of IMMP1L protein aims to elucidate its functional mechanisms, elucidate its interactions with mitochondrial substrates, and explore its potential as a therapeutic target. Recombinant IMMP1L has allowed for in-depth biochemical and structural studies, which are essential for understanding its role in mitochondrial biogenesis and pathology. The insights gained from these studies could pave the way for novel therapeutic strategies for diseases stemming from mitochondrial dysfunction, making IMMP1L a protein of increasing interest in the field of mitochondrial biology and medicine.
