Analytical Data
-
Gene name
IGKC
- Application
-
Alternative Names
Ig kappa chain C region CUM. Ig kappa chain C region EU. Ig kappa chain C region OU. Ig kappa chain C region ROY. Ig kappa chain C region TI
-
Species
Human
-
Source
E. coli
-
Tag
GST-tag at N-terminal
-
Purity
Greater than 90% as determined by SDS-PAGE.
-
Uniprot
P01834
-
Expression Region
1-236aa
-
AA Sequence
METPAQLLFLLLLWLPDSTGENVLTQSPGTLSLSPGERATLSCRASQSLSSSYLAWYQQKPGQAPRLLIYGVSSRATGIPDRFSGSGSGTDFTLTISRLEPEDFAVYYCQQYGTSRPITFGQGTRLDIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC
-
Molecular Weight
51.7 kDa
-
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
-
Form
Freeze-dried powder
-
Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
-
Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
The study of IGKC (Immunoglobulin Kappa Constant) recombinant proteins has gained significant attention due to their crucial role in the immune response and potential therapeutic applications. IGKC encodes the constant region of immunoglobulin kappa light chains, integral components of antibody structure that contribute to the specificity and functionality of B cell responses. Understanding IGKC is essential for comprehending how antibodies are formed and how they interact with antigens. Recombinant protein production techniques allow researchers to create specific IGKC variants, facilitating studies on the structure-function relationships of antibodies and their interaction with immune cells. These recombinant proteins can be employed in various applications, including the development of new vaccines, diagnostics, and therapies, particularly for diseases like cancer and autoimmune disorders. Furthermore, advances in recombinant DNA technology have enabled the optimization of IGKC expression systems, leading to improved yields and functionality of the proteins. By dissecting the role of IGKC in antibody formation and function, researchers aim to harness its potential in enhancing immune responses and developing innovative biotherapeutics. As the field continues to evolve, there is a growing interest in exploring the implications of IGKC-based research in personalized medicine and targeted therapies.
