Analytical Data
-
Gene name
GPR84
- Application
-
Alternative Names
GPR84；EX33；G-Protein coupled receptor 84
-
Species
Human
-
Source
E. coli
-
Tag
His tag N-Terminus
-
Purity
Greater than 90% as determined by SDS-PAGE.
-
Uniprot
Q9NQS5
-
Expression Region
1-26aa
-
AA Sequence
MWNSSDANFSCYHESVLGYRYVAVSW
-
Molecular Weight
31.2 kDa
-
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
-
Form
Freeze-dried powder
-
Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
-
Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
GPR84 is a G protein-coupled receptor (GPCR) belonging to the class A rhodopsin family, which has garnered significant interest in recent years due to its role in various physiological processes and potential implications in diseases. Initially identified as a receptor activated by medium-chain fatty acids, GPR84 has been implicated in immune responses, particularly in the activation of macrophages and the regulation of inflammatory processes. Research has shown that GPR84 is upregulated in a variety of pathological conditions, including inflammatory diseases, neurodegenerative disorders, and certain types of cancer. This has led to an increasing focus on the receptor as a potential therapeutic target. Understanding the structure and function of recombinant GPR84 proteins is crucial for elucidating the underlying mechanisms of its signaling pathways. The expression of GPR84 as a recombinant protein provides a valuable tool for biochemical and pharmacological studies, allowing researchers to investigate ligand binding, receptor activation, and downstream signaling events. Such studies can pave the way for the development of GPR84-targeted therapies aimed at modulating its activity in disease contexts, thus further highlighting the importance of GPR84 in both basic research and clinical applications.
