Analytical Data
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Gene name
HHEX
- Application
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Alternative Names
HHEX;HEX;PRH;PRHX;Hematopoietically-expressed homeobox Protein HHEX
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q03014
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Expression Region
1-270aa
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AA Sequence
MGSSHHHHHH SSGLVPRGSH MGSMQYPHPG PAAGAVGVPL YAPTPLLQPA HPTPFYIEDI LGRGPAAPTP APTLPSPNSS FTSLVSPYRT PVYEPTPIHP AFSHHSAAAL AAAYGPGGFG GPLYPFPRTV NDYTHALLRH DPLGKPLLWS PFLQRPLHKR KGGQVRFSND QTIELEKKFE TQKYLSPPER KRLAKMLQLS ERQVKTWFQN RRAKWRRLKQ ENPQSNKKEE LESLDSSCDQ RQDLPSEQNK GASLDSSQCS PSPASQEDLE SEISEDSDQE VDIEGDKSYF NAG
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Molecular Weight
32 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
HHEX (hematopoietically expressed homeobox) is a transcription factor that plays a crucial role in embryonic development and cell differentiation, particularly in the hematopoietic and vascular systems. As a member of the homeobox gene family, HHEX is essential in the regulation of gene expression during key developmental processes. Research has shown that HHEX is involved in various biological functions, including hematopoiesis, organogenesis, and even cancer progression. Abnormal expression or mutations of HHEX have been associated with various pathologies, including congenital disorders and malignancies, making it a significant focus of investigation in developmental biology and oncology. The study of HHEX recombinant proteins enables researchers to dissect its functional domains, elucidate mechanisms of DNA binding, and understand its interactions with other proteins within the cellular context. These investigations not only enhance our comprehension of HHEX's role in normal physiological processes but also provide insights into its potential as a therapeutic target in diseases associated with dysregulated gene expression and developmental anomalies. Overall, the exploration of HHEX and its recombinantly expressed proteins is vital for advancing our understanding of transcriptional regulation and its implications in health and disease.
