Analytical Data
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基因名
HTR1E
- Application
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别名
HTR1E; 5-hydroxytryptamine receptor 1E; 5-HT-1E; 5-HT1E; S31; Serotonin receptor 1E
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P28566
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表达区间
206-276aa
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氨基酸序列
YHAAKSLYQKRGSSRHLSNRSTDSQNSFASCKLTQTFCVSDFSTSDPTTEFEKFHASIRIPPFDNDLDHPG
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分子量
33.55 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
HTR1E is a member of the 5-hydroxytryptamine (serotonin) receptor family, specifically belonging to the 5-HT1 receptor subtype. This receptor is primarily expressed in the central nervous system and plays a crucial role in various physiological processes, including mood regulation, anxiety, and the modulation of neurotransmitter release. Research into HTR1E has gained momentum due to its potential implications in neuropsychiatric disorders such as depression, anxiety disorders, and schizophrenia. The recombinant expression of HTR1E protein allows for detailed investigations into its structure, function, and pharmacological properties. By producing the protein in non-native systems, researchers can study receptor-ligand interactions, signaling pathways, and the receptor's role in downstream effects on neuronal activity. Understanding the molecular mechanisms of HTR1E could lead to the development of novel therapeutic agents targeting this receptor, offering hope for improved treatments for mental health conditions. Additionally, the study of HTR1E might provide insights into the evolutionary aspects of the serotonin receptor family, as variations in its expression and function may contribute to individual differences in behavior and susceptibility to mental health disorders. Overall, the exploration of HTR1E and its recombinant protein forms is vital for uncovering potential therapeutic targets and elucidating the neurobiological underpinnings of mood and anxiety disorders.












