Analytical Data
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基因名
CATHL1
- Application
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别名
CATHL1；BAC1；Cathelicidin-1
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种属
Bovine
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P22226
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表达区间
144-155aa
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氨基酸序列
RLCRIVVIRVCR
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分子量
30.4 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
CATHL1 (Cationic Antimicrobial Peptide with a CATHL1 Domain) is a member of the cathelicidin family, known for its role in innate immunity, particularly in host defense against microbial infections. Its antimicrobial properties and ability to modulate immune responses have drawn significant interest in biomedical research. The study of CATHL1 recombinant protein is driven by its potential applications in therapeutic strategies, particularly in treating infections caused by antibiotic-resistant bacteria. Research has shown that CATHL1 exhibits broad-spectrum antimicrobial activity, not only against bacteria but also fungi and viruses, making it a candidate for developing novel antimicrobial agents. Furthermore, CATHL1 has been linked to wound healing and tissue regeneration, highlighting its multifunctional roles in the body. Understanding the structure-function relationship of CATHL1 through recombinant protein studies allows researchers to optimize its properties for therapeutic use, assess its effectiveness in various biological contexts, and explore its mechanisms of action in immune modulation. As antibiotic resistance continues to pose a significant global health threat, the exploration of CATHL1 and its recombinant forms may pave the way for innovative solutions in antimicrobial therapy and enhance the understanding of host-pathogen interactions.
