Analytical Data
-
Gene name
HMG14
- Application
-
Alternative Names
HMGN1;HMG14;Non-histone chromosomal Protein HMG-14
-
Species
Human
-
Source
E. coli
-
Tag
His tag N-Terminus
-
Purity
Greater than 90% as determined by SDS-PAGE.
-
Uniprot
P05114
-
Expression Region
1-100aa
-
AA Sequence
MPKRKVSSTEGAAKEEPKRRSARLSAKPPAKVEAKPKKAAAKDKSSDKKV QTKGKRGAKGKQAEVANQETKEDLPAENGETKTEESPASDEAGEKEAKSD
-
Molecular Weight
37 kDa
-
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
-
Form
Freeze-dried powder
-
Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
-
Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
HMG14 (High Mobility Group Protein 14) is a nuclear protein that plays a crucial role in various cellular processes, including chromatin structure regulation, gene expression, and DNA repair. Its involvement in these fundamental biological functions links it to key cellular mechanisms, such as transcriptional regulation and cellular response to stress. Research into HMG14 has gained attention due to its potential implications in cancer biology and development, as aberrations in chromatin remodeling and gene regulation are often implicated in tumorigenesis. Additionally, studies have shown that HMG14 interacts with DNA and other nuclear proteins, influencing chromatin architecture and facilitating the binding of transcription factors to specific gene promoters. Given its critical functions, recombinant HMG14 protein has become a valuable tool for investigating its biochemical properties and interactions in vitro. These recombinant proteins are utilized to explore the mechanistic pathways by which HMG14 influences gene expression and cellular behavior, thus contributing to our understanding of its biological significance. Furthermore, the development of high-yield expression systems for producing HMG14 allows for practical applications in therapeutic development and molecular research, reinforcing the necessity for continued exploration of this protein in the context of both basic biology and potential clinical applications.
