Analytical Data
-
Gene name
GSTM3
- Application
-
Alternative Names
GSTM3;GST5;Glutathione S-transferase Mu 3
-
Species
Human
-
Source
E. coli
-
Tag
His tag N-Terminus
-
Purity
Greater than 90% as determined by SDS-PAGE.
-
Uniprot
P21266
-
Expression Region
1-225aa
-
AA Sequence
MGSSHHHHHH SSGLVPRGSH MGSHMSCESS MVLGYWDIRG LAHAIRLLLE FTDTSYEEKR YTCGEAPDYD RSQWLDVKFK LDLDFPNLPY LLDGKNKITQ SNAILRYIAR KHNMCGETEE EKIRVDIIEN QVMDFRTQLI RLCYSSDHEK LKPQYLEELP GQLKQFSMFL GKFSWFAGEK LTFVDFLTYD ILDQNRIFDP KCLDEFPNLK AFMCRFEALE KIAAYLQSDQ FCKMPINNKM AQWGNKPVC
-
Molecular Weight
29 kDa
-
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
-
Form
Freeze-dried powder
-
Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
-
Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
GSTM3, a member of the glutathione S-transferase (GST) family, plays a crucial role in cellular detoxification processes by catalyzing the conjugation of glutathione to various electrophilic compounds, thereby aiding in their excretion. The study of GSTM3 is particularly relevant due to its implications in drug metabolism, environmental toxin clearance, and the modulation of oxidative stress. Research has shown that variations in GSTM3 expression and activity can influence susceptibility to certain diseases, including cancer and neurodegenerative disorders, as well as individual responses to chemotherapy. Due to these significant implications, constructing recombinant GSTM3 protein is essential for elucidating its biochemical properties, understanding its role in various pathological conditions, and exploring its potential as a therapeutic target. In this context, recombinant techniques allow for the production of sufficient quantities of GSTM3 for functional assays, structural studies, and potential applications in drug design. Overall, GSTM3 represents a vital area of research with the potential for significant contributions to both basic and applied biomedical sciences.
