Analytical Data
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基因名
GSTM3
- Application
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别名
GSTM3;GST5;Glutathione S-transferase Mu 3
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P21266
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表达区间
1-225aa
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氨基酸序列
MGSSHHHHHH SSGLVPRGSH MGSHMSCESS MVLGYWDIRG LAHAIRLLLE FTDTSYEEKR YTCGEAPDYD RSQWLDVKFK LDLDFPNLPY LLDGKNKITQ SNAILRYIAR KHNMCGETEE EKIRVDIIEN QVMDFRTQLI RLCYSSDHEK LKPQYLEELP GQLKQFSMFL GKFSWFAGEK LTFVDFLTYD ILDQNRIFDP KCLDEFPNLK AFMCRFEALE KIAAYLQSDQ FCKMPINNKM AQWGNKPVC
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分子量
29 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
GSTM3, a member of the glutathione S-transferase (GST) family, plays a crucial role in cellular detoxification processes by catalyzing the conjugation of glutathione to various electrophilic compounds, thereby aiding in their excretion. The study of GSTM3 is particularly relevant due to its implications in drug metabolism, environmental toxin clearance, and the modulation of oxidative stress. Research has shown that variations in GSTM3 expression and activity can influence susceptibility to certain diseases, including cancer and neurodegenerative disorders, as well as individual responses to chemotherapy. Due to these significant implications, constructing recombinant GSTM3 protein is essential for elucidating its biochemical properties, understanding its role in various pathological conditions, and exploring its potential as a therapeutic target. In this context, recombinant techniques allow for the production of sufficient quantities of GSTM3 for functional assays, structural studies, and potential applications in drug design. Overall, GSTM3 represents a vital area of research with the potential for significant contributions to both basic and applied biomedical sciences.
