Analytical Data
-
基因名
GSKIP
- Application
-
别名
GSKIP;C14orf129;GSK3B-interacting Protein
-
种属
Human
-
表达系统
E. coli
-
标签
His tag N-Terminus
-
纯度
Greater than 90% as determined by SDS-PAGE.
-
蛋白编号
Q9P0R6
-
表达区间
1-139aa
-
氨基酸序列
MGSSHHHHHHSSGLVPRGSHMETDCNPMELSSMSGFEEGSELNGFEGTDM KDMRLEAEAVVNDVLFAVNNMFVSKSLRCADDVAYINVETKERNRYCLEL TEAGLKVVGYAFDQVDDHLQTPYHETVYSLLDTLSPAYREAFGNALLQRL EALKRDGQS
-
分子量
18 kDa
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
-
性状
Freeze-dried powder
-
缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
-
稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
GSKIP, or Glycogen Synthase Kinase 3 Interacting Protein, has garnered significant attention in recent years due to its role in modulating key signaling pathways associated with cellular growth and differentiation. Emerging research has highlighted GSKIP as a critical regulator of glycogen synthase kinase 3 (GSK3), a pivotal enzyme involved in a variety of cellular processes, including metabolism, gene expression, and apoptosis. Given GSK3's involvement in numerous diseases, including cancer, neurodegenerative disorders, and metabolic syndromes, understanding the structural and functional properties of GSKIP is crucial. Recombination-derived GSKIP proteins enable scientists to dissect its interactions with GSK3 and other cellular components, providing insights into the mechanistic underpinnings of GSK3-related pathways. Additionally, GSKIP's potential as a therapeutic target raises the need for in-depth investigations into its biochemical properties and the development of targeted interventions. Consequently, the study of GSKIP recombination proteins not only enhances our understanding of cellular signaling networks but also paves the way for novel therapeutic strategies in treating conditions where GSK3 activity is dysregulated.
