Analytical Data
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基因名
HKE2
- Application
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别名
H2 KE2; H2KE2; HKE2; HLA class II region expressed gene KE2; KE 2; KE2; KE2 protein; KE2. mouse. homolog of; PFD6_HUMAN; Pfdn6; Prefoldin subunit 6; Protein Ke2
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
O15212
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表达区间
1-129aa
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氨基酸序列
MAELIQKKLQGEVEKYQQLQKDLSKSMSGRQKLEAQLTENNIVKEELALLDGSNVVFKLLGPVLVKQELGEARATVGKRLDYITAEIKRYESQLRDLERQSEQQRETLAQLQQEFQRAQAAKAGAPGKA
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分子量
39.93 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
HKE2, a recombinant protein derived from the human sodium/potassium ATPase alpha-2 subunit, has gained attention in biomedical research due to its significant role in various physiological and pathological processes. It is known to participate in ion transport across cell membranes, which is crucial for maintaining cellular homeostasis and electrical excitability in tissues such as muscle and nerve. The therapeutic potential of HKE2 is particularly noteworthy in cardiovascular diseases, as it is involved in the modulation of cardiac contractility and heart rhythm. Additionally, HKE2 has been implicated in cancer biology, where its expression levels may correlate with tumor progression and patient prognosis. Recent studies have focused on elucidating the detailed mechanisms of HKE2's action and its interactions with other cellular components. By employing advanced techniques such as recombinant DNA technology, researchers are able to produce HKE2 in various expression systems, facilitating the exploration of its structural and functional properties. Understanding HKE2’s multifaceted roles could lead to novel therapeutic strategies targeting ion transport dysregulation in diseases, highlighting the importance of this protein in both fundamental biology and clinical applications.
