Analytical Data
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基因名
HIST2H2AA
- Application
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别名
H2a 615; H2A; H2A GL101; H2A histone family member A; H2A.1; H2A.2; H2A/a; H2A/m; H2A/O; H2A/q; H2A1B_HUMAN; H2AFA; H2AFE; H2AFL; H2AFM; H2AFO; H2AFQ; HIST1H2AE; HIST1H2AJ; HIST2H2AA; HIST2H2AA3; HIST2H2AB; HIST2H2AC; Histone 1 H2ae; Histone 2 H2aa3; Histone 2 H2ab; Histone 2 H2ac; Histone H2A type 1 B; Histone H2A type 1 C; Histone H2A type 1 E; Histone H2A type 1 J; Histone H2A type 1-B/E; Histone H2A.2; Histone H2A/a; Histone H2A/m; MGC74460
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P04908
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表达区间
1-130aa
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氨基酸序列
MSGRGKQGGKARAKAKSRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYMAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGKVTIAQGGVLPNIQAVLLPKKTESHHKAKGK
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分子量
40.04 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
HIST2H2AA is a member of the histone H2A family, specifically involved in the regulation of chromatin structure and gene expression. Histones, including HIST2H2AA, play a crucial role in DNA packaging within the nucleus, allowing for the efficient organization and accessibility of genetic material. Research on HIST2H2AA has gained importance due to its potential implications in various biological processes, such as cell cycle regulation, DNA repair, and epigenetic modifications. The aberrant expression of histone proteins has been linked to several diseases, including cancer, making the study of HIST2H2AA particularly relevant in understanding tumorigenesis and identifying new therapeutic targets. Moreover, advancements in recombinant protein technology have enabled researchers to produce and analyze HIST2H2AA more effectively, providing insights into its structural and functional properties. Investigating the role of HIST2H2AA in chromatin dynamics and its interactions with other nuclear proteins is essential for uncovering its specific contributions to cellular function and stability, paving the way for potential applications in gene therapy and regenerative medicine. By exploring the biophysical characteristics and biological roles of HIST2H2AA, scientists aim to develop targeted strategies that can modulate its activity for therapeutic purposes.
