Analytical Data
-
Gene name
GLTPD1
- Application
-
Alternative Names
GLTPD1；GLTPD1;Ceramide-1-phosphate transfer Protein
-
Species
Human
-
Source
E. coli
-
Tag
His tag N-Terminus
-
Purity
Greater than 90% as determined by SDS-PAGE.
-
Uniprot
Q5TA50
-
Expression Region
1-214aa
-
AA Sequence
MDDSETGFNL KVVLVSFKQC LDEKEEVLLD PYIASWKGLV RFLNSLGTIF SFISKDVVSK LRIMERLRGG PQSEHYRSLQ AMVAHELSNR LVDLERRSHH PESGCRTVLR LHRALHWLQL FLEGLRTSPE DARTSALCAD SYNASLAAYH PWVVRRAVTV AFCTLPTREV FLEAMNVGPP EQAVQMLGEA LPFIQRVYNV SQKLYAEHSL LDLP
-
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
-
Form
Freeze-dried powder
-
Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
-
Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
GLTPD1 (Glycolipid Transfer Protein Domain Containing 1) has emerged as a protein of significant interest due to its potential roles in lipid metabolism, cellular signaling, and membrane composition. Originally identified as a member of the glycolipid transfer protein family, GLTPD1 is thought to facilitate the transport of specific lipids between membranes, thereby influencing various cellular processes, including membrane dynamics and integrity. Recent studies have suggested that GLTPD1 may be implicated in the regulation of neuronal development and function, as well as in various pathological conditions such as cancer and neurodegenerative diseases. Understanding the structure and function of recombinant GLTPD1 protein is crucial for elucidating its biological roles and mechanisms. This research focuses on the production and characterization of GLTPD1 recombinant protein to investigate its lipid-binding properties, interaction with other cellular components, and its overall contribution to lipid homeostasis. By employing advanced techniques such as X-ray crystallography, NMR spectroscopy, and lipid extraction assays, scientists aim to clarify the specific interactions GLTPD1 has with different lipid species and how these interactions influence cellular behavior. Given the potential pathological implications of altered GLTPD1 function, this research may uncover novel therapeutic targets and strategies for diseases associated with lipid metabolism dysregulation. As the field continues to explore the multifaceted roles of GLTPD1, a deeper understanding of its biochemical characteristics will undoubtedly contribute to our knowledge of lipid biology and its implications in health and disease.
