Analytical Data
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基因名
GLTP
- Application
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别名
GLTP;Glycolipid transfer Protein
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9NZD2
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表达区间
1-209aa
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氨基酸序列
MGSSHHHHHHSSGLVPRGSHMGSMALLAEHLLKPLPADKQIETGPFLEAV SHLPPFFDCLGSPVFTPIKADISGNITKIKAVYDTNPAKFRTLQNILEVE KEMYGAEWPKVGATLALMWLKRGLRFIQVFLQSICDGERDENHPNLIRVN ATKAYEMALKKYHGWIVQKIFQAALYAAPYKSDFLKALSKGQNVTEEECL EKIRLFLVNYTATIDVIYEMYTQMNAELNYKV
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分子量
26 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
The study of GLTP (glycolipid transfer protein) recombinant proteins has gained significant attention in recent years due to their crucial role in cellular lipid metabolism and membrane dynamics. GLTP is involved in the transport of glycosphingolipids between membrane compartments, a process essential for cell signaling, membrane biogenesis, and the maintenance of cellular lipid homeostasis. Dysregulation of lipid transport mechanisms can lead to various diseases, including neurodegenerative disorders and cancer. Researchers have focused on the structural and functional characterization of GLTP to better understand its mechanism of action and the implications of its activity in health and disease. The use of recombinant protein technology allows for the production of purified GLTP in adequate quantities, facilitating detailed biochemical and biophysical studies. These investigations are aimed at deciphering the protein's binding affinities, transport mechanisms, and conformational changes upon ligand binding. Additionally, the potential therapeutic applications of GLTP, such as developing modulators that can correct lipid transport deficiencies or targeting GLTP in cancer treatment, represent a burgeoning area of research. Overall, the exploration of GLTP recombinant proteins contributes to a deeper understanding of lipid biology and opens avenues for novel therapeutic strategies.
