Analytical Data
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Gene name
PDCD2
- Application
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Alternative Names
PDCD2；RP8；ZMYND7；Programmed cell death Protein 2
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q16342
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Expression Region
1–344aa
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AA Sequence
MAAAGARPVELGFAESAPAWRLRSEQFPSKVGGRPAWLGAAGLPGPQALACELCGRPLSFLLQVYAPLPGRPDAFHRCIFLFCCREQPCCAGLRVFRNQLPRKNDFYSYEPPSENPPPETGESVCLQLKSGAHLCRVCGCLGPKTCSRCHKAYYCSKEHQTLDWRLGHKQACAQPDHLDHIIPDHNFLFPEFEIVIETEDEIMPEVVEKEDYSEIIGSMGEALEEELDSMAKHESREDKIFQKFKTQIALEPEQILRYGRGIAPIWISGENIPQEKDIPDCPCGAKRILEFQVMPQLLNYLKADRLGKSIDWGILAVFTCAESCSLGTGYTEEFVWKQDVTDTP
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Molecular Weight
44.6 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
PDCD2 (Programmed Cell Death 2) is a crucial regulatory protein involved in various cellular processes, including apoptosis and immune responses. Its role in cell regulation has garnered interest due to its implications in cancer and autoimmune diseases. PDCD2 is known to be predominantly expressed in hematopoietic tissues and plays a significant role in the development and function of immune cells. Research has shown that PDCD2 can interact with several transcription factors and modulate gene expression, influencing cell survival and proliferation. Given its involvement in critical pathways, recombinant PDCD2 protein has become a valuable tool in elucidating molecular mechanisms underlying these processes. The production of PDCD2 as a recombinant protein allows researchers to explore its structural and functional properties more effectively, aiding in the development of potential therapeutic strategies targeting PDCD2-related pathways. Understanding the precise roles of PDCD2 in cellular contexts may pave the way for innovative treatments for diseases wherein PDCD2 is implicated, making it a significant focus of ongoing biomedical research.
