Analytical Data
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Gene name
FOSL2
- Application
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Alternative Names
FOSL2；FRA2FOR20;Fos-related antigen 2
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P15408
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Expression Region
1-326aa
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AA Sequence
MGSSHHHHHH SSGLVPRGSH MGSMYQDYPG NFDTSSRGSS GSPAHAESYS SGGGGQQKFR VDMPGSGSAF IPTINAITTS QDLQWMVQPT VITSMSNPYP RSHPYSPLPG LASVPGHMAL PRPGVIKTIG TTVGRRRRDE QLSPEEEEKR RIRRERNKLA AAKCRNRRRE LTEKLQAETE ELEEEKSGLQ KEIAELQKEK EKLEFMLVAH GPVCKISPEE RRSPPAPGLQ PMRSGGGSVG AVVVKQEPLE EDSPSSSSAG LDKAQRSVIK PISIAGGFYG EEPLHTPIVV TSTPAVTPGT SNLVFTYPSV LEQESPASPS ESCSKAHRRS SSSGDQSSDS LNSPTLLAL
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Molecular Weight
38 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
FOS-like antigen 2 (FOSL2) is a member of the Fos family of transcription factors and plays a critical role in various biological processes, including cell proliferation, differentiation, and apoptosis. It is implicated in several physiological and pathological conditions, including cancer progression and immune responses. Understanding the function of FOSL2 is essential as it is often overexpressed in a variety of tumors, contributing to tumorigenesis and metastasis. Recent studies have highlighted its potential as a therapeutic target, given its involvement in the regulation of genes associated with cancer cell survival and inflammation. Researchers are increasingly focusing on characterizing FOSL2 through recombinant protein studies to elucidate its molecular mechanisms and interactions with other cellular components. This involves the production of FOSL2 recombinant proteins to facilitate functional assays, structural analysis, and the development of inhibitors that could modulate its activity. By investigating FOSL2's role in signaling pathways and its impact on gene expression, scientists aim to uncover novel insights that could lead to new therapeutic strategies for cancers where FOSL2 is a key player. The study of FOSL2 thus represents a vital intersection of molecular biology and therapeutic innovation, potentially contributing to improved cancer treatment outcomes.
