Analytical Data
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Gene name
FOPNL
- Application
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Alternative Names
FOPNL；C16orf63；FOPNL；PSM;Centrosomal Protein 20
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q96NB1
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Expression Region
1-174aa
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AA Sequence
MGSSHHHHHH SSGLVPRGSH MATVAELKAV LKDTLEKKGV LGHLKARIRA EVFNALDDDR EPRPSLSHEN LLINELIREY LEFNKYKYTA SVLIAESGQP VVPLDRQFLI HELNAFEESK DNTIPLLYGI LAHFLRGTKD GIQNAFLKGP SLQPSDPSLG RQPSRRKPMD DHLRKEEQKS TNIEDLHVSQ AVNR
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Molecular Weight
22 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
FOPNL, or Fused in Sarcoma (FUS) and Polyadenylate Binding Protein Nuclear Localization (FOPNL), is a protein implicated in various cellular processes, including RNA metabolism and transcription regulation. Its significance has been underscored in studies linking dysregulation of FOPNL to neurological disorders and cancers, highlighting its potential as a therapeutic target. Research has focused on understanding its structural and functional characteristics, particularly through the exploration of recombinant protein expression techniques. Using advanced biotechnological approaches, researchers have successfully produced FOPNL in microbial systems, allowing for in-depth functional assays and structural analyses. This recombinant production facilitates the study of FOPNL’s interactions with RNA and other proteins, essential for elucidating its role in cellular homeostasis and disease mechanisms. Additionally, understanding FOPNL's structure-function relationship may provide insights into the molecular basis of disorders associated with its dysfunction. Overall, the study of recombinant FOPNL is pivotal for advancing our knowledge of its biological significance and therapeutic potential.
