Cat: PA1000-9761

Recombinant Human MT1E Protein,His

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Analytical Data

  • 基因名

    MT1E

  • Application

    SPRMSTBLIITCELISA细胞实验药物筛选

  • 别名

    MT1E;Metallothionein-1E

  • 种属

    Human

  • 表达系统

    E. coli

  • 标签

    His tag N-Terminus

  • 纯度

    Greater than 90% as determined by SDS-PAGE.

  • 蛋白编号

    P04732

  • 表达区间

    4-59aa

  • 氨基酸序列

    NCSCATGGSCTCAGSCKCKECKCTSCKKSCCSCCPVGCAKCAQGCVCKGASEKCSC

  • 分子量

    32.5 kDa

  • 内毒素

    < 1.0 EU per μg protein as determined by the LAL method.

  • 性状

    Freeze-dried powder

  • 缓冲液

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • 复溶方法

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • 个性化定制

    点位突变 标签定制 buffer定制 全长蛋白定制

  • 稳定性测试

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • 保存条件 & 期限

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • 运输条件

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

MT1E, a member of the metallothionein family, is a low-molecular-weight, cysteine-rich protein involved in metal ion homeostasis and detoxification. Research on MT1E has gained traction due to its significant role in cellular protection against heavy metal toxicity and oxidative stress. Studies have shown that MT1E can bind various heavy metals, such as cadmium and zinc, facilitating their removal or storage in cells, which is crucial for maintaining cellular metal balance. Additionally, the expression of MT1E has been linked to various physiological and pathological conditions, including cancer, neurodegenerative diseases, and inflammation. Its dysregulation can lead to increased sensitivity to oxidative damage and metal-induced toxicity, highlighting the importance of understanding its biological function and regulation. Recent advances in recombinant technology have enabled the production of MT1E in various host systems, facilitating detailed functional and structural studies. These insights open new avenues for therapeutic applications, particularly in developing strategies for metal detoxification and enhancing stress resistance in both plant and animal models. The ongoing investigation into the diverse roles of MT1E continues to reveal its potential as a biomarker for environmental exposure to heavy metals and its promising prospects in biomedical research.

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Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
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