Analytical Data
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Gene name
MT1
- Application
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Alternative Names
MT1；Metallothionein-1X
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P04731
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Expression Region
1-59aa
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AA Sequence
MDPNCSCATGGSCTCTGSCKCKECKCTSCKKSCCSCCPMSCAKCAQGCICKGASEKCSC
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Molecular Weight
32.9 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
MT1 (Metallothionein 1) is a low-molecular-weight protein characterized by its high cysteine content, which facilitates its ability to bind metal ions. First identified as a response to metal exposure, MT1 plays a crucial role in metal homeostasis, detoxification, and protection against oxidative stress. Research on MT1 has expanded significantly due to its potential implications in various physiological and pathological processes, including cancer, neurodegenerative diseases, and diabetes. Elevated levels of MT1 have been observed in certain tumors, suggesting its role as a biomarker for cancer progression and a potential target for therapeutic intervention. Additionally, studies indicate that MT1 may have neuroprotective effects, highlighting its importance in neuronal health and potential as a treatment strategy for neurological disorders. Investigating the mechanisms of MT1’s action, its regulation under different environmental stresses, and its interaction with other cellular pathways is critical for understanding its versatile functions in both health and disease. The exploration of MT1 also opens avenues for biotechnological applications, including its use in bioremediation and as an agent in metal recovery processes. Overall, the study of MT1 is vital for revealing insights into metalloprotein biology and developing innovative strategies for disease intervention and environmental sustainability.
