Analytical Data
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基因名
FAM49B
- Application
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别名
FAM49B；CYRI；FAM49B;CYFIP-related Rac1 interactor B
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9NUQ9
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表达区间
1-324aa
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氨基酸序列
MGSSHHHHHH SSGLVPRGSH MGSMGNLLKV LTCTDLEQGP NFFLDFENAQ PTESEKEIYN QVNVVLKDAE GILEDLQSYR GAGHEIREAI QHPADEKLQE KAWGAVVPLV GKLKKFYEFS QRLEAALRGL LGALTSTPYS PTQHLEREQA LAKQFAEILH FTLRFDELKM TNPAIQNDFS YYRRTLSRMR INNVPAEGEN EVNNELANRM SLFYAEATPM LKTLSDATTK FVSENKNLPI ENTTDCLSTM ASVCRVMLET PEYRSRFTNE ETVSFCLRVM VGVIILYDHV HPVGAFAKTS KIDMKGCIKV LKDQPPNSVE GLLNALRYTT KHLNDETTSK QIKSMLQ
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分子量
39 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
FAM49B, a member of the FAM49 gene family, has garnered attention in the field of molecular biology due to its potential roles in various physiological and pathological processes. Research indicates that FAM49B may be involved in cell proliferation, differentiation, and immune responses, making it a candidate for further investigation in cancer biology and autoimmune diseases. The protein is suspected to interact with key signaling pathways, including those linked to inflammation and cell survival, which suggests it could play a crucial role in maintaining cellular homeostasis. Studies have shown that altered expression levels of FAM49B are associated with several malignancies, raising questions about its potential as a biomarker for cancer diagnosis and prognosis. Furthermore, the protein's function has yet to be fully elucidated, prompting the need for the development of recombinant FAM49B proteins for experimental studies. Utilizing recombinant techniques allows researchers to produce purified FAM49B, facilitating investigations into its biochemical properties, interactions, and functional implications in various cellular contexts. These studies could uncover new insights into the molecular mechanisms driving diseases and identify potential therapeutic targets. Overall, the exploration of FAM49B and its recombinant variants represents a promising avenue of research with the potential to contribute significantly to our understanding of complex biological systems and the development of innovative treatment strategies.
