Analytical Data
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基因名
GPSM1
- Application
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别名
Activator of G-protein signaling 3; AGS3; AGS3 homolog ; C10a; G protein signaling modulator 1 (AGS3 like; C. elegans) ; G-protein-signaling modulator 1; GPSM1; GPSM1_HUMAN
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q86YR5
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表达区间
1-675aa
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氨基酸序列
MAGPAPPVAD ELPGPAARRL YSRMEASCLE LALEGERLCK AGDFKTGVAF FEAAVQVGTE DLKTLSAIYS QLGNAYFYLK EHGRALEYHK HDLLLARTIG DRMGEAKASG NLGNTLKVLG RFDEAAVCCQ RHLSIAQEQG DKVGEARALY NIGNVYHAKG KQLSWNAANA TQDPGHLPPD VRETLCKASE FYERNLSLVK ELGDRAAQGR AYGNLGNTHY LLGNFTEATT FHKERLAIAK EFGDKAAERR AYSNLGNAHV FLGRFDVAAE YYKKTLQLSR QLRDQAVEAQ ACYSLGNTYT LLQDYERAAE YHLRHLLIAQ ELADRVGEGR ACWSLGNAYV SMGRPAQALT FAKKHLQISQ EIGDRHGELT ARMNVAQLQL VLGRLTSPAA SEKPDLAGYE AQGARPKRTQ RLSAETWDLL RLPLEREQNG DSHHSGDWRG PSRDSLPLPV RSRKYQEGPD AERRPREGSH SPLDSADVRV HVPRTSIPRA PSSDEECFFD LLTKFQSSRM DDQRCPLDDG QAGAAEATAA PTLEDRIAQP SMTASPQTEE FFDLIASSQS RRLDDQRASV GSLPGLRITH SNAGHLRGHG EPQEPGDDFF NMLIKYQSSR IDDQRCPPPD VLPRGPTMPD EDFFSLIQRV QAKRMDEQRV DLAGGPEQGA GGPPEPQQQC QPGAS
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分子量
74.5 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
GPSM1, or G-protein signaling modulator 1, is a protein that plays a crucial role in the regulation of G-protein coupled receptor (GPCR) signaling pathways, which are essential for various physiological processes. Research on GPSM1 has gained attention in the context of cellular signaling, as it modulates G-protein activation and influences various downstream effects, including cell proliferation, differentiation, and apoptosis. This protein is particularly noteworthy because of its involvement in neurological functions and its potential implications in neurodegenerative diseases. Studies have indicated that alterations in GPSM1 expression or function may contribute to disorders such as Alzheimer's Disease and schizophrenia, making it a target of interest for therapeutic interventions. Furthermore, GPSM1's role in cancer biology is also under investigation, as aberrant GPCR signaling has been linked to tumor progression and metastasis. Thus, understanding the molecular mechanisms of GPSM1 and its impact on G-protein signaling could provide valuable insights into both normal physiological processes and pathological conditions, highlighting the need for comprehensive research into its structure, function, and potential as a biomarker or therapeutic target.
