Analytical Data
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Gene name
ARG
- Application
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Alternative Names
ARG；ARFGAP1；ADP-ribosylation factor GTPase-activating Protein 3
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q8N6T3
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Expression Region
1-406aa
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AA Sequence
MASPRTRKVLKEVRVQDENNVCFECGAFNPQWVSVTYGIWICLECSGRHRGLGVHLSFVRSVTMDKWKDIELEKMKAGGNAKFREFLESQEDYDPCWSLQEKYNSRAAALFRDKVVALAEGREWSLESSPAQNWTPPQPRTLPSMVHRVSGQPQSVTASSDKAFEDWLNDDLGSYQGAQGNRYVGFGNTPPPQKKEDDFLNNAMSSLYSGWSSFTTGASRFASAAKEGATKFGSQASQKASELGHSLNENVLKPAQEKVKEGKIFDDVSSGVSQLASKVQGVGSKGWRDVTTFFSGKAEGPLDSPSEGHSYQNSGLDHFQNSNIDQSFWETFGSAEPTKTRKSPSSDSWTCADTSTERRSSDSWEVWGSASTNRNSNSDGGEGGEGTKKAVPPAVPTDDGWDNQNW
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Molecular Weight
45.5 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
The study of ARG (Arginase) recombinant proteins is rooted in the critical role that arginase plays in the metabolic pathway of arginine, an essential amino acid. Arginase catalyzes the hydrolysis of arginine into ornithine and urea, thus influencing nitrogen metabolism as well as nitric oxide synthesis. Given its involvement in various physiological processes, alterations in arginase activity have been implicated in numerous pathological conditions, including cardiovascular diseases, neurodegenerative disorders, and cancer. The production of recombinant ARG proteins allows for detailed characterization of their enzymatic functions and regulatory mechanisms, facilitating the development of targeted therapeutic approaches. These recombinant proteins can be used to elucidate the role of arginase in different tissues, study its interaction with other metabolic pathways, and assess its potential as a biomarker or therapeutic target. Furthermore, advancements in genetic engineering and protein expression systems have improved the yield and functionality of these proteins, making them valuable tools in basic and clinical research. By advancing our understanding of arginase’s multifunctional roles, researchers can explore innovative strategies for manipulating its activity to enhance health outcomes and therapeutic interventions.
